Full cast of What's New, Scooby-Doo?

Frank Welker

Fred Jones / Scooby-Doo (voice)

42 episodes

Casey Kasem

Shaggy Rogers (voice)

42 episodes

Mindy Cohn

Velma Dinkley (voice)

42 episodes

Grey DeLisle

Daphne Blake (voice)

42 episodes

James Arnold Taylor

Burr Batson / Champ Truman (voice) / Frankie Martin / Shawn (voice) / Prince Qasl Al-Famir / Tourist Son (voice) / Dr. Laslow Ostwald / Tad (voice) / The Scientist (voice) / Sonny Les Matines / Guy L'Avorton (voice) / Owen DeCassle / Steve Fortescu (voice)

8 episodes

Dee Bradley Baker

Faceless Phantom / Bull Brassman / Assistant Director (voice) / Menacing Metallic Clown / Gary Snipper (voice) / Crusty McPete / Lighthouse Keeper (voice) / Chinese Dragon (voice) / Skull / Announcer / M'Lady Moonbeam (voice) / Mike (voice) / Snow Creature (voice) / Fish Fiend (voice)

8 episodes

Jeff Bennett

Earnest Bailey / Burglar #1 / Worker #1 (voice) / Roderick Kingston / Writer (voice) / Mr. B / Scar / Guard (voice) / Mr. B (voice) / Sam / Tailor / Swedish Fan (voice) / General Niedermeyer / Mr. B / MP Guard #1 (voice) / Feta Cheese Vendor / Major Portsmouth / Shop Owner (voice) / Charles 'Crunchy' Granville / Fritz / Mr. Keenan (voice)

8 episodes

Jennifer Hale

Sue Krose (voice) / Linda / Gooey-Oh Creature / Zombie Kid #3 (voice) / Thorn (voice) / Meadow / Maize / Knox (voice) / Leora Lasswell (voice) / House Computer / Allison (voice) / Honey Hunsecker / Dr. Joan Goodfew (voice)

7 episodes

John DiMaggio

Glasburgh Dragon / Officious Dwarf / Judge (voice) / Malachi Crunch / Titanic Twist (voice) / Sanfran Psycho (voice) / Taylor Leland / Police Officer (voice) / Mike Fury (voice)

5 episodes

Steve Blum

Rufus Raucous (voice) / J.T. Page / Steve Powell (voice) / Melbourne O’Reilly (voice) / Melbourne O'Reilly / Guide (voice) / Rama Yam / Spencer Johnson (voice)

5 episodes

Tom Kenny

Jack Hunter (voice) / Sam / Harry Harrison (voice) / Clown / Haunted House / Cougar Forest (voice) / Natlas (voice) / Band Member / Curtis / Fair Headed Boy (voice)

5 episodes

Lauren Tom

Nancy Chang (voice) / Heather Lane (voice) / Mandy Dinwiddie (voice)

4 episodes

Kevin Michael Richardson

Lloyd Mbuku / Safari Member / Henry Huncecker (voice) / Sharky Tazo / Stink Eye (voice) / Bruce Wilkenson (voice) / Announcer / Red Guy (voice)

4 episodes

Kimberly Brooks

Luna (voice) / Janet Lawerence / Elliott Binder (voice) / Elliott Binder (voice) / Phylidia Flanders / Backup Singer #2 (voice)

4 episodes

Colleen O'Shaughnessey

Jingle (voice) / Celia Clyde (voice)

4 episodes

Eddie Deezen

Gibby Norton (voice)

3 episodes

Tara Strong

Trudy Lowe (voice) / Terry / Joe (voice) / Alexandra Viggi (voice)

3 episodes

Rob Paulsen

Avery Orenthal / Government Agent (voice) / Travis Knox / MP Guard / PA Announcer (voice) / Jamison Steven Ripley / Pan Lute Player / Puny Guy (voice)

3 episodes

Daran Norris

Camel Sam / Tourist Dad (voice) / Cowardly Lion / Mr. Reed / Sheriff (voice) / Ugo DiRinaldi / Shopkeeper (voice)

3 episodes

Fred Tatasciore

Skeleton (voice) / Clyde / Toxic Terror (voice) / Cat Creature (voice)

3 episodes

Nick Jameson

Stu Fortescu / Wrenchfield (voice) / Rebel Canyon (voice) (uncredited) / Lysander Demas / Scary Looking Man (voice)

3 episodes

Jim Cummings

Broderick Bosepheus / Humongus Hammer (voice) / Cyrus T. Buford / Crawdad Mike / Joe (voice)

2 episodes

Tasia Valenza

Lupe Chesares / Wormian #2 (voice) / Brooke Bjork (voice)

2 episodes

Brian Tochi

J.J. Hakimoto (voice) / Hakimoto (voice)

2 episodes

Pamela Adlon

Chris / Eddie (voice) / Janey / Bobby Blather (voice)

2 episodes

Phil LaMarr

Col. Henry Thomwald / Shaman (voice) / Toddy Stickfigger / Cabbie (voice)

2 episodes

Roger Rose

Sparrow Man / P.A. Announcer (voice) / Narrator / Policeman (voice)

2 episodes

Carlos Alazraqui

Roberto Torres / Jaime Herrera / Motor Cross Guy #1 (voice) / Luis Santiago / Umpire (voice)

2 episodes

Mark Hamill

Barge Captain (voice) / Tommy's Father (voice)

2 episodes

Taylor Lautner

Ned (voice) / Dennis (voice)

2 episodes

Rachael MacFarlane

Sheila (voice) / Connie Crunch / Spice (voice)

2 episodes

Rino Romano

Captain Treesdale / Keith Dale (voice) / Coral Creature (voice)

2 episodes

Kevin McDonald

Julian Libris (voice) / Walter Claphammer (voice)

2 episodes

Frankie Ryan Manríquez

Ernie (voice) / Jimmy (voice)

2 episodes

John Stephenson

Zelig (voice) / Bob Taylor (voice)

2 episodes

John O'Hurley

Beavis Bottomczek (voice) / Mayor Snipper (voice)

2 episodes

William Schallert

Farmer P. / Neville Popenbacher (voice) / Professor Pomfrit (voice)

2 episodes

Jane Wiedlin

Dusk (voice) / Backup Singer #1

2 episodes

Stacy Keach

The Mayor (voice) / Harold Ling (voice)

2 episodes

Michael Gough

Drill Sergeant Payne / MP Guard (voice) / Vampire (voice)

2 episodes

John Gabriel

Dr. Zola / Worker (voice) / P.A. Announcer (voice)

2 episodes

Moira Quirk

Susie Smythe (voice) / Mei Ling (voice)

2 episodes

Greg Ellis

Detective Kang (voice) / Russian PA Announcer / Nicolai / Bob (voice)

2 episodes

Lindsay Pagano

Self (voice)

1 episode

Kath Soucie

Susan Dinwiddie (voice)

1 episode

Brian Unger

Avalanche Anderson (voice)

1 episode

Héctor Elizondo

Dr. Gutierrez (voice)

1 episode

Dave Foley

Laslow Oswald (voice)

1 episode

Bumper Robinson

Cap N' Robbie / Native Bearer (voice)

1 episode

Larc Spies

Andy Dinwiddie (voice)

1 episode

Jesse Borrego

Luis Cepeda (voice)

1 episode

Kerrigan Mahan

Del Stone (voice)

1 episode

Rip Taylor

Mr. Wackypants (voice)

1 episode

Jason Harris

Flapjack / Announcer (voice)

1 episode

Josh Peck

Damian / Kid / Zombie Kid #2 (voice)

1 episode

Chris Klug

Self (voice)

1 episode

Mimi Rogers

Maura Ravenmane / Helga (voice)

1 episode

Daryl Sabara

Tommy / Steve (voice)

1 episode

Matt Levin

Ticket Taker / Matt (voice)

1 episode

David Faustino

Curt Crunch (voice)

1 episode

Laraine Newman

Wor-El (voice)

1 episode

Corey Burton

Gusano Grande (voice)

1 episode

Jess Harnell

Lute Player / Shane Flinty / Constable (voice)

1 episode

Beng Spies

Murph / Randy Dinwiddie (voice)

1 episode

Irene Bedard

Cody Long (voice)

1 episode

Michael Horse

Leon Strongfeather (voice)

1 episode

Billy West

Jimmy Proudwolf (voice)

1 episode

Vanessa Marshall

Danica LeBlake (voice)

1 episode

Jim Belushi

Asa Buckwald (voice)

1 episode

Kathy Kinney

Sheriff Ellen Perkins (voice)

1 episode

Peter Scolari

Professor Higginson (voice)

1 episode

M. Emmet Walsh

Jeb (voice)

1 episode

Teri Garr

Sandy Gordon (voice)

1 episode

Bill Mumy

Harry Noze (voice)

1 episode

Eddie Santiago

Chip Hernandez, Jr. (voice)

1 episode

Gedde Watanabe

Vincent Wong (voice)

1 episode

Kathy Griffin

Autumn Summerfield (voice)

1 episode

Mike Piazza

Self (voice)

1 episode

Clyde Kusatsu

Dr. Akira Onodera / Fisherman / Desk Clerk (voice)

1 episode

Mako

The Ancient One (voice)

1 episode

Gwendoline Yeo

Lt. Keiko Tanaka (voice)

1 episode

Benito Martinez

Horatio Hidalgo (voice)

1 episode

Jonathan Osser

Billy Blather (voice)

1 episode

Diedrich Bader

Uncle Evan (voice)

1 episode

Jenny McCarthy

Marcy (voice)

1 episode

Rhea Perlman

Agnes (voice)

1 episode

Paul Stanley

Self (voice)

1 episode

Julia Sweeney

Aunt Meg (voice)

1 episode

DeeDee Rescher

Sylvie (voice)

1 episode

Ryan Sheckler

Self (voice)

1 episode

Nika Futterman

Rutie Banez (voice)

1 episode

Maurice LaMarche

Haze Ferlenguini / Security Guy (voice)

1 episode

Pierre Bouvier

Self (voice)

1 episode

Chuck Comeau

Self (voice)

1 episode

David Desrosiers

Self (voice)

1 episode

Sébastien Lefebvre

Self (voice)

1 episode

Jeff Stinco

Self (voice)

1 episode

Vince Corazza

Zeke Zillion (voice)

1 episode

Susanne Blakeslee

Penelope Bailey (voice)

1 episode

Larry Drake

Moss T. Meister / Burglar #2 / Scooby Snax Monster (voice)

1 episode

Eva Almos

Captain Corvina Cloyd (voice)

1 episode

Mikey Kelley

Monroe Hopper (voice)

1 episode

Kathy Nagler

Sergeant Linda Rauch (voice)

1 episode

Paul Julian

Road Runner (voice) (archive footage) (uncredited)

1 episode

Pat Fraley

Uncle Karl (voice)

1 episode

James Horan

Dr. Fleg / Bandit (voice)

1 episode

Joey Lauren Adams

Rachel (voice)

1 episode

Dan Castellaneta

Officer McBride / Police Officer (voice)

1 episode

Harland Williams

George (voice)

1 episode

JC Chasez

Self (voice)

1 episode

Simon Petrie

Jonas Sulk / Demon Farmer (voice)

1 episode

Jill Talley

Frida Flora (voice)

1 episode

Ron Perlman

Inspector Malpumpkin / Joe / Frozen Fiend (voice)

1 episode

Brett Hull

Self (voice)

1 episode

Miranda Cosgrove

Miranda Wright / Stacy (voice)

1 episode

Stacie Chan

Alex (voice)

1 episode

Tara Lipinski

Grey (voice)

1 episode

Denzel Whitaker

Jake / Kid (voice)

1 episode

James Sie

Louie Hong Fa (voice)

1 episode

Victoria Bruno

Cindy (voice)

1 episode

Rodger Bumpass

Announcer / Steve (voice)

1 episode

Steve Harwell

Self (voice)

1 episode

Ben Diskin

Benji / Travis / Zombie Kid #1 (voice)

1 episode

Khary Payton

Mitch (voice)

1 episode