Full cast of The Big C

Laura Linney

Cathy Jamison

40 episodes

John Benjamin Hickey

Sean Tolkey

40 episodes

Oliver Platt

Paul Jamison

40 episodes

Gabriel Basso

Adam Jamison

40 episodes

Phyllis Somerville

Marlene

15 episodes

Gabourey Sidibe

Andrea Jackson

14 episodes

Phill Lewis

Cool pool boss

13 episodes

Michael Chernus

Pastor Rick

4 episodes

Emily Kinney

Emily

3 episodes

Brian d'Arcy James

Tim

3 episodes

Liz Holtan

Amber

2 episodes

Judy Gold

Rabbi

1 episode

Rebecca Watson

Blonde Woman (uncredited)

1 episode

E.J. Bonilla

Scott

1 episode

Angela Lewis

Day Nurse

1 episode

Cynthia Nixon

Rebecca

1 episode

Reid Scott

Todd Mauer

1 episode

Ned Eisenberg

Dr. Volimer

1 episode

Ann Harada

Brenda

1 episode

Jessica Cummings

Second Receptionist

1 episode

John Hillner

Doctor

1 episode

Anne Senelly Kyle

Cancer Patient (uncredited)

1 episode

Jeremy McLain

Pedestrian (uncredited)

1 episode

Brian Dennehy

Dad

1 episode

Isaac Mizrahi

Self

1 episode

Kathy Najimy

Cathy's Therapist

1 episode

Connie Ray

Connie Schuler

1 episode

Darlene Hunt

Hospice Administrator

1 episode

Michael Ray Escamilla

Angel

1 episode

Bianca Amato

Susan Rand

1 episode

Marceline Hugot

Ina

1 episode

David Aaron Baker

Priest

1 episode

David Wilson Barnes

Wesley

1 episode

Marin Mazzie

Janelle Milson

1 episode

Jen Sese

Florist

1 episode

Rosemary Howard

Hospice Visitor (uncredited)

1 episode

Marisa R. Silver

Fashion Show Guest (uncredited)

1 episode