Full cast of Big Mouth

Nick Kroll

Nick Birch / Maury the Hormone Monster / Coach Steve / Lola Skumpy / Rick the Hormone Monster (voice)

81 episodes

John Mulaney

Andrew Glouberman (voice)

81 episodes

Jessi Klein

Jessi Glaser (voice)

81 episodes

Jason Mantzoukas

Jay Bilzerian (voice)

81 episodes

Maya Rudolph

Diane Birch / Connie the Hormone Monstress (voice)

81 episodes

Fred Armisen

Elliot Birch (voice)

81 episodes

Jordan Peele

Ghost of Duke Ellington (voice)

81 episodes

Andrew Rannells

Matthew (voice)

59 episodes

Jenny Slate

Missy Foreman-Greenwald (voice)

42 episodes

Joe Wengert

Caleb (voice) / Caleb / Lump Humpman (voice) / Caleb / Rewind Shirt Kid / Go-Gurt Burglar (voice) / Caleb / Go-Gurt Thief / Teacher (voice) / Caleb / Go-Gurt Burglar (voice) / Caleb / Pornscape Residents (voice) / Caleb / IUD (voice) / Caleb / Dot #3 / Leore Paulblart (voice) / Stan the Hormone Monster / Ambition Gremlin (voice) / Teacher (voice) / Mr. Albert (voice) / Steven Tyler Glade Plug-In / Zombie (voice)

33 episodes

Ayo Edebiri

Missy Foreman-Greenwald (voice) / Missy Foreman-Greenwald / Mosaic Missy (voice)

32 episodes

June Diane Raphael

Devin (voice)

25 episodes

Richard Kind

Marty Glouberman (voice)

25 episodes

Jessica Chaffin

Shannon Glaser (voice) / Shannon Glaser / Grace / Intellect Sphinx (voice)

24 episodes

Neil Casey

Lars (voice) / Lars / Detective Dumont / Pornscape Residents (voice) / (voice) / Lars / Jew Penis (voice) / Lars / Rewind Shirt Kid (voice) / Detective Dumont / Lars (voice) / Detective Dumont / D.N. Ape (voice) / Lars / Detective Dumont (voice) / Lars / Boy (voice) / Detective Dumont (voice)

22 episodes

Paula Pell

Barbara Glouberman (voice) / (voice) / Barbara Glouberman / Bubbe (voice) / Barbara Glouberman / Lola's Couch Pillow (voice)

22 episodes

Jon Daly

Judd Birch (voice) / Judd Birch / Pumbaa (voice) / Garrison Keillor / Magician #1 (voice)

21 episodes

Jak Knight

DeVon (voice) / Tall Guy (voice) / DeVon / Gina's Brother #2 (voice) / DeVon

19 episodes

Chelsea Peretti

Monica Foreman-Greenwald (voice) / Cellsea (voice) / Diaphragm (voice)

17 episodes

Seth Morris

Greg Glaser (voice) / (voice) / Ninth Grader (voice)

17 episodes

Gil Ozeri

Wiggles (voice) / (voice) / Brad (voice) / Jew Fishman (voice) / The Ponytail Killer / Pornscape Residents (voice) / Man #1 / Dot #2 (voice)

15 episodes

Mark Rivers

(voice) / Maury's Backup Singer (voice) / Michael Stipe Tampon (voice) / Backup Singer (voice) / Man #2 / Penis Worms (voice) / Ghost of David Bowie (voice) / Vendor (voice) / Siamese Twin #1 (voice)

15 episodes

Nathan Fillion

Nathan Fillion (voice)

15 episodes

Kat Dennings

Leah Birch (voice) / Leah Birch / Lorraine the Hormone Monstress (voice)

15 episodes

Gina Rodriguez

Gina Alvarez (voice) / Gina Alvarez / Gina Parrot (voice)

14 episodes

David Thewlis

Shame Wizard (voice)

13 episodes

Thandiwe Newton

Mona (voice)

13 episodes

Brandon Kyle Goodman

Walter the Lovebug (voice) / Walter (voice)

12 episodes

Maria Bamford

Tito the Anxiety Mosquito (voice)

12 episodes

Heather Lawless

Jenna Bilzerian (voice)

12 episodes

Mark Duplass

Val Bilzerian (voice)

11 episodes

Whitmer Thomas

9 episodes

Paul Scheer

Kurt Bilzerian (voice)

8 episodes

Ali Wong

Ali (voice)

8 episodes

Zachary Quinto

Aiden (voice)

8 episodes

Stephanie Beatriz

Lulu (voice)

8 episodes

Emily Altman

Vicky (voice) / Milk (voice) / (voice) / Olivia / Filmstrip Narrator (voice)

7 episodes

Chloe Fineman

Leah Birch (voice)

7 episodes

Rob Huebel

Mr. Lizer (voice)

6 episodes

Natasha Lyonne

Suzette (voice) / Ms. Dunn (voice)

6 episodes

Gary Cole

Edward MacDell (voice) / Andrew's Father (voice) / Matthew's Father (voice)

6 episodes

Jean Smart

Depression Kitty (voice)

6 episodes

Jack McBrayer

Pubic Hair #1 (voice) / Jack (voice)

6 episodes

John Gemberling

Tyler the Hormone Monster (voice) / Tyler the Hormone Monster / Dot #1 (voice) / Security Guard / Bus Driver's Son (voice)

5 episodes

Craig Robinson

Pubic Hair #2 (voice) / End Credits Singer (voice) / Harvey Brooks (voice) / Craig (voice)

5 episodes

Michaela Watkins

Cantor Dina Reznick (voice)

5 episodes

Fran Gillespie

(voice) / Maddie the American Girl Doll / Choir Girl (voice) / Samira (voice) / Girl (voice)

5 episodes

Kristen Bell

Pam the Pillow (voice) / Uninterested Girl (voice)

4 episodes

Ashley London

Kitty / DNA Expert / Pornscape Residents (voice) / The Virgin Mary / Waitress (voice) / Skank (voice) / (voice)

4 episodes

Zach Woods

Daniel (voice) / Sock (voice)

4 episodes

Rosa Salazar

Ms. Benitez (voice)

4 episodes

Quinta Brunson

Quinta (voice) / Girl (voice)

4 episodes

Ayden Mayeri

Gabrielle / Mellon Ball / Honeydew (voice) / Gabrielle (voice) / Gabrielle / Freshman (voice) / Gabrielle / Sad Boy #2 (voice)

4 episodes

Andy Daly

Dr. Wendy Engle / Motel Pillow #1 (voice) / Dr. Wendy Engle (voice) / Ghost of Harry Houdini (voice)

3 episodes

Bobby Cannavale

Gavin the Hormone Monster (voice) / Nick's Agent (voice) / Gavin (voice)

3 episodes

John Oliver

Harry (voice)

3 episodes

Seth Rogen

Seth Goldberg (voice)

3 episodes

Julie White

Kimberly (voice) / Kimberly MacDell (voice)

3 episodes

Sterling K. Brown

Michael Angelo (voice)

3 episodes

Crissy Guerrero

(voice)

3 episodes

Kristen Wiig

Jessi's Vagina (voice)

3 episodes

Lena Waithe

Lena (voice)

3 episodes

Megan Thee Stallion

Megan the(e?) Hormone Monstress (voice)

3 episodes

Patrick Page

Dread (voice)

3 episodes

Ileen Goldsmith

Jessi Glaser - singing double / Judd's Girlfriend (voice) / (voice)

2 episodes

Brendan McCreary

Freddie Mercury (singing voice) / Ghost of Freddie Mercury (voice)

2 episodes

Carlos Alazraqui

Gustavo (voice)

2 episodes

Julie Klausner

Cherry Marashina (voice)

2 episodes

Chris Redd

(voice)

2 episodes

Josie Totah

Natalie (voice)

2 episodes

Joel Kim Booster

Charles Lu (voice)

2 episodes

Judd Hirsch

Lewis Glouberman (voice)

2 episodes

Beck Bennett

Owen (voice)

2 episodes

Billy Porter

Ocean (voice)

2 episodes

J Valerione

B-High Qee-Choi Member (voice)

2 episodes

Keke Palmer

Rochelle the Hate Worm (voice)

2 episodes

Aidy Bryant

Emmy (voice)

2 episodes

Rosie Perez

Petra (voice)

2 episodes

Mitra Jouhari

2 episodes

Juliet Mills

2 episodes

Pamela Adlon

Sonya the Lovebug (voice)

1 episode

Jon Hamm

Scallops (voice)

1 episode

Jon Gabrus

Movie Theater Customer (voice)

1 episode

Anna Graves

Mrs. Albert (voice)

1 episode

Nasim Pedrad

Fatima (voice)

1 episode

Mae Whitman

Tallulah Levine (voice)

1 episode

Chrissy Guerrero

Choir Girl (voice)

1 episode

Philip Quinaz

Tanya Alvarez (voice)

1 episode

Harvey Fierstein

Older Guy Town Resident (voice)

1 episode

Jerry Minor

Man #3 / Singing Fish (voice)

1 episode

Piotr Michael

Siamese Twin #2 (voice)

1 episode

Marisa Lark Wallin

Reese's Wertherspoon / Woman (voice)

1 episode

Martin Short

Gordie (voice)

1 episode

David Cross

Skip Glouberman (voice)

1 episode

Carol Kane

Menopause Banshee / Old Woman (voice)

1 episode

Tawny Newsome

(voice)

1 episode

Retta

Duke's Mother (voice)

1 episode

Wanda Sykes

Ghost of Harriet Tubman (voice)

1 episode

Jaboukie Young-White

(voice)

1 episode

Rob Riggle

Sgt. Adderall (voice)

1 episode

Bobby Berk

Bobby Berk (voice)

1 episode

Karamo Brown

Karamo Brown (voice)

1 episode

Tan France

Tan France (voice)

1 episode

Antoni Porowski

Antoni Porowski (voice)

1 episode

Jonathan Van Ness

Jonathan Van Ness (voice)

1 episode

Anna Konkle

Izzy (voice)

1 episode

Maya Erskine

Misha (voice)

1 episode

Alia Shawkat

Roland (voice)

1 episode

Paul Giamatti

Andrew’s Shit (voice)

1 episode

Adam Scott

Mr. Dylan Keating (voice)

1 episode

Hugh Jackman

himself (voice)

1 episode

Kumail Nanjiani

himself (voice)

1 episode

Jemaine Clement

Simon Sex (voice)

1 episode

Kristen Schaal

Bernie Sanders (voice)

1 episode

Somali Rose

Missy’s Overalls

1 episode

Lupita Nyong'o

Asha (voice)

1 episode

Miranda Tapsell

Kara (voice)

1 episode

Lin-Manuel Miranda

Puerto Rican Pubic Hair (voice)

1 episode

Randall Park

Pete Doheny (voice)

1 episode

Maitreyi Ramakrishnan

Marissa (voice)

1 episode

Ava Lalezarzadeh

Nazanin (voice)

1 episode

Don Cheadle

Don Cheadle (voice)

1 episode

Padma Lakshmi

Priya (voice)

1 episode

Zach Galifianakis

Gratitoad (voice)

1 episode

Jeff Goldblum

The Apple Brooch

1 episode

Steve Buscemi

1 episode

Skyla I'Lece

1 episode

Katie Kreshek

1 episode

Violet Rivers

1 episode

Larry Owens

1 episode

Holly Hunter

1 episode

James III

1 episode

Franny London

1 episode

Cynthia Erivo

1 episode

Andrew Goldberg

1 episode

Eliseo Román

Eliseo Román (voice)

1 episode